Helping The others Realize The Advantages Of ceesdekker.net
Helping The others Realize The Advantages Of ceesdekker.net
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Halfway by his profession, Cees Dekker reinvented himself. After yrs of hardcore physics, he shifted his target to ‘nanobiology’ within the change of the millennium. A expression he coined himself, to be a issue of point.
Human Rad51 filaments on double- and one-stranded DNA: correlating normal and irregular varieties with recombination function.
[Laughs] ‘It had been undoubtedly a fantastic threat! At time, I was well aware that it could go Completely wrong Which I could develop into a lot less productive, but I just dismissed that. Curiosity has always been my strongest driving drive. And fortunately all of it worked out.’
2007, initially genuine-time detection of strand Trade in homologous recombination by RecA; discovery of the reduced persistence size of finishes of microtubules; and resolved the mechanism of biosensing with carbon nanotubes
2010, produced a different way (‘wedging transfer’) to govern nanostructures; first report of DNA translocation via graphene nanopores; and realized hybrid nanopores by directed insertion of α-hemolysin into sound-condition nanopores
Experimental phase diagram of negatively supercoiled DNA calculated by magnetic tweezers and fluorescence,
A lot of linked developments adopted, wherever our team recognized distinctive transistor variants such as one-electron transistors at room temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled multiple transistors into small evidence-of-basic principle Digital circuits.
Studying DNA loop extrusion by SMC proteins for chromosome architecture with one-molecule assays.
‘Of course, I comprehend persons had been amazed at some time. At the end of the nineties, Once i was in my forties, I had been Professor of Molecular Electronics and I have to admit that it experienced turn into a bit bored, I didn’t understand A great deal any more. The sector went more into the appliance aspect, how you could integrate nanotubes into electronic circuits.
But carbon nanotubes have remained a research matter of sizeable desire to quite a few. In fact, the outlook on applying carbon nanotubes to make realistic equipment, in areas including radio-frequency electronics, digital electronics and flexible electronics, continues to be brilliant.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij satisfied enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever design in 2005. (nl)